5 Simple Statements About LDN-27219 cancer treatment research Explained
One particular specially appealing compound is LDN-27219. Whilst most tTG inhibitors are intended to bind into the protein crosslinking Energetic internet site, LDN-27219 alternatively binds to your nucleotide binding pocket on the enzyme although it's in its shut-state conformation, and stabilizes that conformation to prevent crosslinking activity